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Image Search Results
Journal: Hippocampus
Article Title: Somatostatin Depresses the Excitability of Subicular Bursting Cells: Roles of Inward Rectifier K + Channels, KCNQ channels and Epac
doi: 10.1002/hipo.22744
Figure Lengend Snippet: PKA and PKC are not required for SST-elicited outward HCs, but Epac2 is partially involved. A, Application of Rp-cAMPS (200 μM) via the recording pipettes did not block SST-mediated outward HCs. B, Inclusion of PKI(5-24) (2 μM) in the recording pipettes failed to alter SST-induced outward HCs. C, Pretreatment of slices with and inclusion of H89 (10 μM) in the recording pipettes did not block SST-evoked outward HCs. D, Pretreatment of slices with and inclusion of KT 5720 (5 μM) in the recording pipettes did not block SST-elicited outward HCs. E, Pretreatment of slices with and inclusion of GF109203X (2 μM) in the recording pipettes failed to block SST-elicited outward HCs. F, Pretreatment of slices with and inclusion of HJC0350 (100 μM) in the recording pipettes reduced SST-induced outward HCs. G, Summery graph.
Article Snippet: PKI(
Techniques: Blocking Assay